2-(3-Aminoaryl)amino-4-aryl-thiazoles for the treatment of...

Details 2-(3-Aminoaryl)amino-4-aryl-thiazoles for the treatment of... 2-(3-Aminoaryl)amino-4-aryl-thiazoles for the treatment of...

2003-08-01

2008-09-09

Stockton, Laura L. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S370000, C546S270400, C548S194000, C544S364000

Reexamination Certificate

active

07423055

ABSTRACT:
The present invention relates to novel compounds selected from 2-(3-aminoaryl)amino-4-aryl-thiazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.

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