Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-03-03
1980-03-25
Randolph, John D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546288, 546300, A61K 3144, C07D21346
Patent
active
041950909
ABSTRACT:
Heterocyclic compounds of the formula ##STR1## wherein Het denotes optionally substituted pyridazinyl, pyrimidinyl, pyrazinyl or substituted pyridyl, R.sub.1 is hydrogen or methyl and R.sub.2 is lower alkyl, optionally substituted phenyl-lower alkyl, carboxy-lower alkyl or functionally modified carboxy-lower alkyl, their condensation products with aldehydes, ketones or carbonic acid and their N-oxides, which are valuable (cardioselective) .beta.-rezeptor blocking agents, and/or (cardioselective) .beta.-rezeptor-stimulants.
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Kerwin et al, J. Am. Chem. Soc. vol. 73, pp. 4162-4168 (1951).
Frei Jurg
Jaeggi Knut A.
Ostermayer Franz
Schroter Herbert
Ciba-Geigy Corporation
Maitner John J.
Randolph John D.
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