2,3,5-substituted biphenyls useful in the treatment of...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C549S471000, C562S512000, C562S587000, C548S335100, C548S469000, C548S470000, C546S339000, C514S469000, C514S416000, C514S415000, C514S396000, C514S354000, C514S571000

Reexamination Certificate

active

07008636

ABSTRACT:
This invention provides compounds of Formula I having the structureor a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.

REFERENCES:
patent: 3394193 (1968-07-01), Reppe et al.
patent: 3666473 (1972-05-01), Colom et al.
patent: 3800051 (1974-03-01), Barnhart et al.
patent: 4117151 (1978-09-01), Descamps et al.
patent: 4147659 (1979-04-01), De Jonge et al.
patent: 4613611 (1986-09-01), Floyd, Jr. et al.
patent: 4808599 (1989-02-01), Dubroeucq et al.
patent: 5235064 (1993-08-01), Gapinski
patent: 5334598 (1994-08-01), Bagley et al.
patent: 5523302 (1996-06-01), Cain et al.
patent: 5596106 (1997-01-01), Cullinan et al.
patent: 5688821 (1997-11-01), Kees
patent: 5698574 (1997-12-01), Riedl et al.
patent: 5753687 (1998-05-01), Mjalli et al.
patent: 1 249 869 (1967-09-01), None
patent: 1 291 197 (1969-03-01), None
patent: 26 16 414 (1977-10-01), None
patent: 31110460 (1982-12-01), None
patent: 33 42 624 (1984-03-01), None
patent: 0 276 064 (1988-07-01), None
patent: 0 568 289 (1993-11-01), None
patent: 0 693 491 (1996-01-01), None
patent: 1 248 107 (1971-09-01), None
patent: 1 293 396 (1972-10-01), None
patent: 1 450 005 (1976-09-01), None
patent: 58150948 (1983-09-01), None
patent: 60172946 (1985-09-01), None
patent: 62036661 (1987-02-01), None
patent: 62036662 (1987-02-01), None
patent: 63161449 (1988-07-01), None
patent: 3247655 (1991-11-01), None
patent: 4016854 (1992-01-01), None
patent: 6348018 (1994-12-01), None
patent: WO 91/11909 (1991-08-01), None
patent: WO 94/22834 (1994-10-01), None
patent: WO 94/22835 (1994-10-01), None
patent: WO 96/08483 (1996-03-01), None
patent: WO 96/09818 (1996-04-01), None
patent: WO 96/34851 (1996-11-01), None
patent: WO 97/08934 (1997-03-01), None
patent: WO 97/21693 (1997-06-01), None
patent: WO 97/39748 (1997-10-01), None
Levin, P. et al.: Flash photolysis study of phenyl-substituted phenols, quinones, and corresponding free radicals.J.C.S. Perkins Transactions 2, vol. 9, pp. 1237-1239, 1981.
Kessler, M. et al.: An improved synthesis of the solvatochromic dye ET-30. Synthesis, vol. 8, pp. 635-636, 1988.
Compounds with RN 33661-81-3, 63671-76-1, 40410-91-1, 20104-41-0 and 186901-80-4. disclosed prior to 1995.
Ahmad et al., Biochemica et Biophysica Acta, 1995, 57-69, 1248.
Chang et al., Diabetes, 1983, 830-838, 32.
Coleman et al., Diabetologia, 1978, 141-148, 14.
DeFronzo et al., Diabetes Care, 1991, 173-194, 14(3).
Goldstein, Receptor, 1993, 1-15, 3.
Goldstein et al., Mol. and Cell. Biochem., 1992, 107-113, 109.
Goldstein, Cell. Biochem., 1992, 33-42, 48.
Haring, Diabetolgia, 1991, 848-861, 34.
Harris et al., Diabetes in America, 1985, 1-48, Ch. 29.
Jarrett, Diabetes/Metabolism Reviews, 1989, 547-558, 5(7).
Lanzetta et al., Analytical Biochem., 1979, 95-97, 100.
McGuire et al., Diabetes, Jul. 1991, 939-942, 40.
Meyerovitch et al., J. Clin. Invest., Apr. 1991, 1286-1294, 87.
Meyerovitch et al., J. Clin. Invest., Sep. 1989, 976-983, 84.
Mitsunobu, Synthesis, Jan. 1981, 1-28.
Nutaitis, Organic Preparations and Procedures Int., 1991, 403-411, 23(4).
Perlich et al., Synthesis, Feb. 1988, 142-144.
Phillon et al., 1986, 1477-1480, 27(13).
Pyorala et al., Diabetes/Metabolism Reviews. 1987, 463-524, 3(2).
Reaven et al., Amer. J. Med., 1976, 80-88, 60.
Stredy et al., Metabolism, 1995, 1074-1081, 44(8).
Stout et al., Metabolism, Dec. 1985, 7-12, 34(2) (Suppl. 1).
Zask et al., J. Med. Chem., 1990, 1418-1423, 33.
Chen et al., Indian J. Chem., Dec. 1996, 1304-1307, 35B.
d'Ischia et al., Tetrahedron, 1987, 431-434, 43(2).
Dryhurst et al., J. Am. Chem. Soc., 1989, 719-726, 111.
Guirguis et al., J. Prakt. Chem. Soc., 1990, 414-418, 332(3).
Guirguis et al., Liebigs Ann. Chem., 1986, 1003-1011.
Han et al., Tetrahedron Letter, 1990, 1181-1182, 31(8).
Hashem et al., J. Prakt. Chemie, 1977, 689-692, 319(4).
Konopelski et al., Synlett Letters, Jul. 1996, 609-611.
Kuroda et al., J. Org. Chem., 1994, 7353-7357, 59.
Kuroda et al., J. Chem. Soc., Chem. Commun., 1991, 1635-1636.
Lefker et al., Tetrahedron Letters, 1994, 5205-5208, 35(29).
Molina et al., Tetrahedron, 1994, 5027-5036, 50(17).
Molina et al., Tetrahedron Letters, 1993, 2809-2812, 34(17).
Napolitano et al., Tetrahedron, 1989, 6749-6760, 45(21).
Schuster et al., J. Org. Chem., 1988, 5819-5825, 53.
Buu-Hoi et al., J. Chem. Soc., 1957, 625-628.
Brown et al., J. Med. Chem., 1971, 84-85, 14(1).
Kimura et al., Tetrahedron Letters, 1995, 1079-1080, 36(7).
Schuster et al., J. Org. Chem., 1988, 5819-5825, 53.
Kano et al., Heterocycles, 1982, 1033-1037, 19(6).
Martin et al., J. Org. Chem., 1984, 2512-2513, 49.
Eckert et al., Arch. Pharm., 1982, 569-570, 315.
Goldenberg et al., Eur. J. Med. Chem., Chim. Ther., Jan.-Feb. 1977, 81-86, 12(1).
Artini et al., Arzneim-Forsch. (Drugs Res.), 1971, 30-36, 21(1).
Ayyangar et al., Synthesis, Apr. 1991, 322-324.
Darchen et al., J.C.S. Chem. Comm., 1976, 820.
DeCointet et al., Chimie Therapeutique, Sep.-Oct. 1973, 574-587, 5.
Hamacher, Arch. Pharmaz., 1975, 290-301, 308.
Massolina et al., Il Farmaco, 1990, 263-268, 45(2).
Miyaura et al., Synthetic Communications, 1981, 513-519, 11(7).
Barraclough et al, Arch Pharm., 1990, 507-512, 323.
Liebeskind et al., J. Org. Chem., 1990, 5359-5364, 55.
Toth, Liebigs Ann Chem., 1994, 685-688.
Watanabe et al., Chem. Abstracts, 1996, 124:116928s.
Abdurasuleva et al., Chem. Abstracts, 1965, 62:10356a.
Richter et al., 1967, 67:21652n.
Kryuchkova et al., Chem. Abstracts, 1961, 55:3488i.
Zavgorodini et al., Chem. Abstracts, 1962, 57:14982ia.
Boit, Beilstein Handbook of Org. Chem., 1966, 1374-1381, 1384, 1749, 3330-3339, 3361-3364, 4thed., 3rdSuppl., vol. VI.
Richter, Beilstein Handbook of Org. Chem., 1933, 183-185, 217, 218, 4thed., 1stSuppl., vols. XIII/XIV.
Luckenbach, Beilstein Handbook of Org. Chem., 1979, 2141-2126, 3268, 3271, 4thed., 4thSuppl., vol. VI.
Aldrich Catalog, 1996, p. 596.
Abdelkader, M. et al. : Synthesis and characterization of a stable poly(iminomethylene) with pendant phenoxyl radicals. Chem. Mater. vol. 3, pp. 598-602, 1991.
Potter, D. et al. : Identification of Acetaminophen polymerization products catalyzed by horseradish peroxidase. J. Biol. Chem. vol. 260, pp. 12174-12180, 1985.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2,3,5-substituted biphenyls useful in the treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2,3,5-substituted biphenyls useful in the treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2,3,5-substituted biphenyls useful in the treatment of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3569172

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.