2,3,4-cyclopentan-2,3,4-triol-1-yl compounds

Details 2,3,4-cyclopentan-2,3,4-triol-1-yl compounds 2,3,4-cyclopentan-2,3,4-triol-1-yl compounds

2005-01-18

2005-01-18

McKenzie, Thomas C. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S230000, C544S254000

Reexamination Certificate

active

06844348

ABSTRACT:
The invention provides a compound of formula (I):wherein R1is alkyl C1-6or alkenyl C2-6, both independently optionally substituted by one or more groups selected from alkyl C1-5or halogen; R2is cycloalkyl C3-8, optionally substituted by R3; R3is phenyl, optionally substituted by one or more groups selected from alkyl C1-6or halogen; R4and R5are alkyl C1-6or together cycloalkyl C3-6. These compounds are useful for the treatment of stable and unstable angina.

REFERENCES:
patent: WO-9905143 (1999-02-01), None
West, Anthony R., “Solid State Chemistry and its Applications”, Wiley, New York, 1988, pp. 358 & 365.*
Patricia Cluttona, John D. Foltsb and Jane E. Freedmana, Pharamcological Research, vol. 44, Issue 4, Oct. 2001, pp. 255-264.*
Storey, R.F. et al, Thromb. Haemost., 2001, 85(3), pp. 401-407, Medline Abstract PMID 11307804.

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