2,3,4,5-tetrahydro-1H-3-benzazepines

Details 2,3,4,5-tetrahydro-1H-3-benzazepines 2,3,4,5-tetrahydro-1H-3-benzazepines

1994-05-06

1995-11-28

Datlow, Philip I.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540594, 540595, C07D40502, C07D40510, A61K 3155

Patent

active

054708508

ABSTRACT:
2,3,4,5-Tetrahydro-1H-3-benzazepines having the general formula ##STR1## wherein R.sup.1 is Cl or Br; R.sup.3 and R.sup.4 are hydrogen, halogen, CF.sup.3, CN, NO.sub.2, or NH.sub.2.
The compounds are useful in treatment of certain disorders in the central nervous system.

REFERENCES:
patent: 4255445 (1981-03-01), Brush et al.
patent: 4751222 (1988-06-01), Braestrup et al.
patent: 5017571 (1991-05-01), Hansen et al.
Anderson et al., Life Science, vol. 37, pp. 1971-1983 (1985).
Hansen et al., Drug Metab. Dispos., vol. 20, No. 2, pp. 172-178 (1992).
Pedersen et al., Acta Pharmacol. Toxicol., vol. 31, pp. 488-496 (1972).

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