2-(2-thienyl)-imidazo(4,5-c)pyridine derivatives and salts there

Details 2-(2-thienyl)-imidazo(4,5-c)pyridine derivatives and salts there 2-(2-thienyl)-imidazo(4,5-c)pyridine derivatives and salts there

1986-09-30

1988-01-19

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546118, A61K 3144, C07D47104

Patent

active

047205016

ABSTRACT:
The invention relates to new 2-(2-thienyl)imidazo(4,5-c)pyridine derivatives of the formula ##STR1## wherein R.sub.1 denotes lower alkyl, R.sub.2 denotes hydrogen or methyl and n denotes 0 or 1, and pharmaceutically usable acid addition salts thereof, a process for their preparation and pharmaceutical products containing these compounds. The new compounds and their salts have useful pharmacological properties, in particular a positively inotropic action on the heart, and can be used as active compounds for medicaments for the treatment of diseases of the heart and vessels, in particular myocardial insufficiency.

REFERENCES:
patent: 4582837 (1986-04-01), Hauel et al.
patent: 4596830 (1986-06-01), Binder et al.

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