2-{[2-(substituted amino)ethyl]sulfonyl}ethyl...

Details 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl... 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl...

2011-01-18

2011-01-18

Andres, Janet L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S413000, C558S169000, C514S089000, C514S091000, C514S118000

Reexamination Certificate

active

07872134

ABSTRACT:
2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates and their salts, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer and autoimmune diseases, alone and in combination with other therapies.

REFERENCES:
patent: 5556942 (1996-09-01), Kauvar et al.
patent: 6506739 (2003-01-01), Herr et al.
patent: 7655799 (2010-02-01), Ma et al.
patent: 2005/0267075 (2005-12-01), Robinson et al.
patent: WO 95/09866 (1995-04-01), None
patent: WO 01/83496 (2001-11-01), None
patent: WO 2005/118601 (2005-12-01), None
Jain M et al., “Sulfonyl-containing aldophosphamide analogues as novel anticancer prodrugs targeted against cyclophosphamide-resistant tumor cell lines”,J. Med. Chem., v.47, pp. 3843-3852, Jul. 15, 2004 (published on Web Jun. 17, 2004).
Tew, K.D. “TLK-286: A novel glutathione S-transferase-activated prodrug.”Expert Opinion on Investigational Drugs, Ashley Publications Ltd., Londn, GB, vol. 14, No. 8, 2005, pp. 1047-1054.
U.S. Appl. No. 11/564,744, Ma et al.

Affiliated with

Also associated with

Rating

2-{[2-(substituted amino)ethyl]sulfonyl}ethyl... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2711458