2-(2-pyridylmethylthio (sulfinyl)) benzimidazoles

Details 2-(2-pyridylmethylthio (sulfinyl)) benzimidazoles 2-(2-pyridylmethylthio (sulfinyl)) benzimidazoles

1986-12-02

1987-08-25

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

046893334

ABSTRACT:
The compound of the formula ##STR1## wherein R.sup.1 is hydrogen, methoxy or trifluoromethyl, R.sup.2 and R.sup.3 are independently hydrogen or methyl, R.sup.4 is a C.sub.2-5 fluorinated alkyl and n denotes 0 or 1, or a pharmacologically acceptable salt thereof is novel, and useful for prophylaxis and therapy of digestive ulcers (e.g. gastric ulcer, duodenal ulcer) and gastritis.

REFERENCES:
patent: 4045563 (1977-08-01), Berntsson et al.
patent: 4255431 (1981-03-01), Junggren et al.
patent: 4472409 (1984-09-01), Senn-Bilfinger

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