2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and deriva

Details 2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and deriva 2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and deriva

1982-11-08

1985-03-19

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40112

Patent

active

045060746

ABSTRACT:
2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and derivatives and acid addition salts thereof generally are selective .alpha..sub.2 -adrenergic receptor antagonists and .alpha..sub.1 -adrenergic receptor agonists and thereby useful as antidepressants and nasal decongestants.

REFERENCES:
patent: 3907816 (1975-09-01), Winkelmann et al.
patent: 4046896 (1977-09-01), Winkelmann et al.
patent: 4078063 (1978-03-01), Lumma et al.
patent: 4376772 (1983-03-01), Saari et al.
patent: 4381302 (1983-04-01), Huff et al.
patent: 4442103 (1984-04-01), Saari
patent: 4456604 (1984-06-01), Saari
Ser. No. 439,698, by Huff et al.
Ser. No. 436,753, by Saari.

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