2-(2-Methyl-5-nitro-1-imidazolyl)ethyl cycloaminocarbodithioates

Details 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl cycloaminocarbodithioates 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl cycloaminocarbodithioates

1974-04-23

1976-05-04

Weinberger, Lorraine A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602471M, 2602937, 424248, 424251, 424267, C07D29514

Patent

active

039547680

ABSTRACT:
2-(2-Methyl-5-nitro-1-imidazolyl)ethyl esters of cycloaminocarbodithioates are herein described. These compounds are anti-protozoal and anti-fungal agents. The compounds are prepared in 2 steps. The reaction of the appropriate cycloamine with carbon disulfide in aqueous base forms the aminocarbodithioate salt and the final products are formed by the reaction of this salt with 1-(2-chloroethyl)-2-methyl-5-nitroimidazole.

REFERENCES:
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patent: 3646027 (1972-02-01), Carlson et al.
patent: 3696116 (1972-10-01), Jeanmart et al.
patent: 3723453 (1973-03-01), Gradnik et al.
patent: 3803165 (1974-04-01), Beaman et al.
patent: 3828065 (1974-08-01), Kreider
Conaut et al., The Chemistry of Organic Compounds, 3rd Ed.; p. 342 (1947).

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