2,2'-disubtituted 1,1'-diphosphino-ferrocenes and 1',2-disubstit

Details 2,2'-disubtituted 1,1'-diphosphino-ferrocenes and 1',2-disubstit 2,2'-disubtituted 1,1'-diphosphino-ferrocenes and 1',2-disubstit

1997-04-24

1999-01-05

Nazario-Gonzalez, Porfirio

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

556 22, 556 28, 556136, 556144, C07F 1702

Patent

active

058565400

ABSTRACT:
The present invention relates to optically active and racemic C.sub.2 -symmetric 2,2'-disubstituted 1,1'-diphosphino-ferrocenes of the formula Ia, to optically active and racemic asymmetric 1',2-disubstituted 1-phosphino-ferrocenes of the formula Ib and to achiral 2,2'-disubstituted 1,1'-diphosphino-ferrocenes of the formula II, to processes for preparing them, especially in accordance with the principle of asymmetric ortho-lithiation, to their use as ligands for transition metal complexes, to transition metal complexes comprising them, and to the use of the transition metal complexes as catalysts, especially in asymmetric syntheses. ##STR1##

REFERENCES:
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Lothar Schwink et al., "A New Practical Asymmetric Synthisis of C.sub.2 -Symmetrical 1,1'-Ferrocenyl Diols vi CBS-Reduction," Tetrahedron Letters, vol. 37, No. 1, pp. 25-28 (1996).
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