2,2 disubstituted glycerol and glycerol-like compounds, composit

Details 2,2 disubstituted glycerol and glycerol-like compounds, composit 2,2 disubstituted glycerol and glycerol-like compounds, composit

1992-10-02

1995-09-12

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514367, 514370, 514 77, 548164, 548194, 548196, 548201, 548204, C07D27782, A61K 31425

Patent

active

054496802

ABSTRACT:
Novel 2,2-disubstituted glycerol-like compounds are disclosed for use as anti-allergic and anti-inflammatory compounds. The compounds are antagonists of platelet activating factor ("PAF"). Also disclosed are methods of synthesizing and using the compounds of the invention as well as pharmaceutical compositions thereof. The compounds have the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as defined in the specification.

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