Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-09-06
1993-02-09
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142358, 5142355, 5142368, 5142372, 5142378, 5142382, 5142388, 5142392, 514 90, 544124, 544132, 544133, 544139, 544141, 544157, 544158, 544159, 544160, 544161, 544164, 544165, 544168, 544169, 544170, 544171, 544177, A61K 3138, A61K 31395, C07D26530, C07D29518, C07D29522
Patent
active
051853345
ABSTRACT:
Novel 2,2-disubstituted glycerol-like compounds are disclosed for use as anti-allergic and anti-inflammatory compounds. The compounds are antagonists of platelet activating factor ("PAF"). Also disclosed are methods of synthesizing and using the compounds of the invention as well as pharmaceutical compositions thereof. The compounds have the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as defined in the specification.
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Ganguly Ashit K.
Kaminski James J.
Lehman de Gaeta Laura S.
Solomon Daniel
White Steven K.
Jeanette Henry C.
Nelson James R.
Richter Johann
Rosen Gerald S.
Schering Corporation
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