Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-11-09
1990-08-14
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514253, 544291, 544364, 544371, 546197, 546199, A61K 31505, C07D40514
Patent
active
049487973
ABSTRACT:
2,2-Disubstituted 2,3-dihydro-1,4-benzodioxin derivatives of formula (I): ##STR1## and pharmaceutically acceptable salts thereof having in vitro high affinity and selectively for .alpha..sub.1 receptors and in vivo good and long lasting hypotensive activty, with negligible side-effects; processes for the preparation thereof and pharmaceutical compositions therefrom.
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patent: 4188390 (1980-02-01), Campbell
patent: 4189484 (1980-02-01), Mizogami et al.
patent: 4287341 (1981-09-01), Hess et al.
patent: 4558129 (1985-12-01), Kluge et al.
patent: 4788290 (1988-11-01), Stack et al.
Manghisi Elso
Salimbeni Aldo
Hollrah Glennon H.
Istituto Luso Farmaco D'Italia S.p.A.
Turnipseed James H.
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