2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process

Details 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process

1995-01-18

1996-05-28

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2711, 536 285, 536 2851, 514 29, C07H 504, C07H 506, C07H 19073

Patent

active

055212948

ABSTRACT:
This invention provides novel 1-alkylsulfonyl-2,2-difluoro-3-carbamoyl ribose intermediates and intermediate nucleosides derived therefrom. The compounds are particularly useful in the preparation of 2'-deoxy-2',2'-difluoro-beta-cytidine and other beta anomer nucleosides which are antiviral and anticancer agents.

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