2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-

Details 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor- 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-

1977-08-01

1978-09-26

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 60, 260408, 260410, 2604105, 2604109R, 260413, 562465, C07C17700

Patent

active

041172337

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Abstract 4723U-B DT-2305044-Q Sep. 8, 1973.
Derwent Abstract 18176Y/11 BG 846-080 Oct. 3, 1977.
Derwent Abstract 61891X/33 DT 2603-172 May 8, 1976.
Derwent Abstract 59715X/32 BE 839-533 Jan. 7, 1976.
Derwent Abst. 79219X/42, U.S. 3984400 May 10, 1976.

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