2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,2 0-trinor

Details 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,2 0-trinor 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,2 0-trinor

1977-08-01

1978-07-04

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260408, 260410, 2604105, 2604109R, 260413, 260520R, 260520B, C07C17700

Patent

active

040990150

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Abstract, 4223U-B DT 2305044-Q (09-08-73).
Derwent Abstract, 18176Y/11 BE 846-080 (10-03-77).
Derwent Abstract, 61891X/33 DT 2603-172 (05-08-76).
Derwent Abstract, 59715X/32 BE 839-533 (01-07-76).
Derwent Abstract, 79219X/42 U.S. 3984,400 (05-10-76).

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