2,2'-bridged bis-2,4-diaminoquinazolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544284, 544291, A01N 4354, C07D40100, C07D23972

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active

058744380

ABSTRACT:
The present invention relates to 2,2'-bridged bis-2,4-diaminoquinazolines of the general formula (I): ##STR1## in which the indicated substituents are as defined in the description. The invention also provides processes for the preparation of the compounds of the formula (I), their use for the preparation of drugs, and drugs containing said compounds.

REFERENCES:
patent: 3956495 (1976-05-01), Lacefield et al.
patent: 4734418 (1988-03-01), Yokoyama et al.
Giardina et al., "Synthesis and .alpha..sub.1 -Antagonist . . . Tetraamine Disulfides." Eur. J. Med. Chem. (1997), vol. 32, pp. 9-20.
Abstract of J6 1140-568-A (English language).
Eur.J.Med.Chem. 12, 1977, 325 (English language).

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