2-(2-Alkynylamino)-3H-1,4-benzodiazepines

Details 2-(2-Alkynylamino)-3H-1,4-benzodiazepines 2-(2-Alkynylamino)-3H-1,4-benzodiazepines

1973-09-10

1976-01-20

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603322R, 2603323P, 2603325, 2603472, 2603473, 2603477, 424244, 424263, 424269, 2602393D, 2602564R, 2602565R, 2602948C, 260295T, 260295K, 260295F, 260296B, 260309, 26032634, 2603265CA, 2603269, 260329S, 260329F, C07D24320, C07D40104

Patent

active

039337944

ABSTRACT:
Novel 6-substituted 4H-imidazo[1,2-a][1,4]benzodiazepines, the intermediate 5-substituted-2-(2-alkynylamino)-3H-1,4-benzodiazepines, pharmacologically acceptable acid addition salts thereof, and processes for their production. The compounds of this invention and the pharmacologically acceptable acid addition salts thereof are central nervous system depressants. They are useful as sedatives, hypnotics, tranquilizers, muscle relaxants and anticonvulsants, and also as feed additives for increasing growth rate and feed efficiency of livestock and poultry, milk production in the mammalian species and egg production in avian species.

REFERENCES:
patent: 2893992 (1959-07-01), Sternbach et al.
patent: 3320239 (1967-05-01), Stempel et al.
patent: 3422091 (1969-01-01), Archer et al.
Sternbach et al., Psychopharmacological Agents, M. Gordon, ed., Vol. I, (Academic Press, 1964), p. 145.

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