2,2,4-trialkyl-1,2-dihydroquinazoline-3-oxides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514267, 544231, 544283, A61K 31505, C07D40304

Patent

active

053267656

ABSTRACT:
Novel 2,2,4-trialkyl-1,2-dihydroquinazoline-3-oxides and their synthesis are described. These compounds possess cardiotonic activity, and are useful for the treatment of heart failure.

REFERENCES:
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patent: 3485841 (1969-12-01), Field et al.
patent: 4963554 (1990-10-01), Combs et al.
Armarego, et al., "Journ. Chem. Soc." C, 1966, pp. 1433-1436.
Walker, et al., "Jour. Org. Chem.", vol. 37, No. 24, 1972 pp. 3755-3770.

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