[2,2,1]Cryptand compounds that selectively bind sodium

Details [2,2,1]Cryptand compounds that selectively bind sodium [2,2,1]Cryptand compounds that selectively bind sodium

1986-11-19

1989-06-27

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540468, C07D49806

Patent

active

048431583

ABSTRACT:
A compound having the property of selectively binding sodium ions in the presence of potassium ions and having the formula: ##STR1## where X is ##STR2## and where any aromatic ring may be substituted and/or may form part of a fused aromatic ring system.
At least one of the aromatic rings may be substituted by a spectroscopic reporter group, a group which permits the compound to enter and remain in a cell and/or an electron donating or withdrawing group.
A method of determining cytoplasmic sodium concentration by using this compound as a probe is also described.

REFERENCES:
Smith et al., CA106-115945m (1987).

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