2-(1-oxo-3-thiolanyl)-2-penem antibiotics

Details 2-(1-oxo-3-thiolanyl)-2-penem antibiotics 2-(1-oxo-3-thiolanyl)-2-penem antibiotics

1987-12-03

1988-12-27

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

548952, C02D40912

Patent

active

047941790

ABSTRACT:
Process and intermediates for the conversion of 3R,4R-4-acetoxy-3-[1R-1-(silyloxy)ethyl]-2-azetidinones to antibacterial 5R,6S-6-(1R-1-hydroxyethyl)-2-(1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids, and the pharmaceutically-acceptable salts and pivaloyloxymethyl esters thereof.

REFERENCES:
patent: 4530793 (1985-07-01), Girijavallabhan et al.
patent: 4619924 (1986-10-01), Hamanaka

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