1H-pyrido-(2,3-b) (1,4)-thiazines

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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544 34, C07D51304

Patent

active

048618780

ABSTRACT:
New potent lipoxygenase inhibitors which are 1H-pyrido-[2,3-b][1,4] thiazines are disclosed. The new thiazines are of the formula ##STR1## in which R.sup.1 denotes hydrogen, halogen, optionally substituted alkyl or alkoxy or the group ##STR2## in which R.sup.5 and R.sup.6 are identical or different and denote hydrogen, optionally substituted alkyl or aryl, or can be linked to form a 5- or 6-membered heterocyclic ring,

REFERENCES:
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Chemical Abstracts, Band 83, Nr. 23, 8. Dezember 1975, Seite 476, Spalte 2, Zusammenfassungs Nr. 193384y; & SU- A - 430 642 (Ordzhonikidze, S., All-Union Scientific-Research Chemical-Pharmaceutical Institute). 25.07.1975.
Safonova et al, CA, vol. 83, 83: 193384y, p. 476, 1975.
Safonova et al, CA, vol. 74, 1971, 74: 141668p.
Shen et al, "The Development of Antiasthma Drug", Part III, ed. D. R. Buckle et al, Butterworth Publishers, Kent, England, 1980, pp. 315-317; 331-335.

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