1H-isoindole-1,3-dione compounds

Details 1H-isoindole-1,3-dione compounds 1H-isoindole-1,3-dione compounds

1994-07-11

1996-03-26

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548485, C07D40106

Patent

active

055022103

ABSTRACT:
The invention relates to intermediate compounds which are useful in the preparation of N-tert-butyl-decahydro-2- 2 (R)-hydroxy-4-phenyl-3(S)-phthalimidobutyl!-(4aS, 8aS)-isoquinoline-3(S)-carboxamide. The final products are suitable for the treatment of vital infections, such as those caused by HIV and other retroviruses.

REFERENCES:
patent: 5196438 (1993-03-01), Martin
Hassal et al., Heterocycles 7:119-122 (1977).
Hassall et al., J. Chem. Soc. Perkin Transactions I, pp. 155-166 (1984).
Ikarya et al., J. Chem. Soc. Chem. Commun., pp. 922-924 (1985).
Parkes et al. J. Org. Chem., vol. 59, 1994, pp. 3656-3664.
Sasai et al. Tetrahedron Letters, vol. 55, No. 33, 1994, pp. 6123-6126.

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