1H-indole-3-glyoxylamide SPLA.sub.2 inhibitors

Details 1H-indole-3-glyoxylamide SPLA.sub.2 inhibitors 1H-indole-3-glyoxylamide SPLA.sub.2 inhibitors

1995-06-06

1997-08-05

Haley, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548492, 548494, 548495, 544373, 514381, C07D40312, C07D20912, A61K 31495, A61K 31405

Patent

active

056543263

ABSTRACT:
A class of novel 1H-indole-3-glyoxylamides is disclosed together with the use of such indole compounds for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock.

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