1H-indole-3-glyoxylamide sPLA.sub.2 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514381, 544373, 548492, 548494, 548495, A61K 31405, A61K 31495, C07D40312, C07D20912

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active

059198109

ABSTRACT:
A class of novel 1H-indole-3-glyoxylamides is disclosed together with the use of such indole compounds for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock.

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