Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-13
1997-06-24
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 91, 548113, 548481, C07D20908, C07F 9553, A61K 3140
Patent
active
056418000
ABSTRACT:
A class of novel 1H-indole-1-functional compounds is disclosed together with the use of such indole compounds for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock. The compounds are 1H-indole-1-acetamides, 1H-indole-1-acetic acid hydrazides, and 1H-indole-1-glyoxylamides.
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Bach Nicholas J.
Dillard Robert D.
Draheim Susan E.
Benjamin Roger S.
Boone David E.
Eli Lilly and Company
Springer David B.
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