1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S221000, C540S556000

Reexamination Certificate

active

07932248

ABSTRACT:
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

REFERENCES:
patent: 7456171 (2008-11-01), Galli et al.
patent: 2 845 388 (2004-04-01), None
patent: WO 2004/016616 (2004-02-01), None
patent: 2004/033456 (2004-04-01), None
patent: WO 2005/063767 (2005-07-01), None
Schmitt et al., Targeting Nicotinic Acetylcholine Receptors: Advances in Molecular Design and Therapies, Annual Reports in Medicinal Chemistry, vol. 35, 2000, pp. 41-51.
Int'l. Search Report and the Written Opinion of the Int'l. Searching Authority, issued Mar. 1, 2007 in PCT/US2006/04318.

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