1H-imidazole derivatives as cannabinoid receptor modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S336100

Reexamination Certificate

active

10965155

ABSTRACT:
The invention relates to a group of 1H-imidazole derivatives which are modulators of cannabinoid receptors, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of said imidazole derivatives, to methods for the preparation of these intermediates, to pharmaceutical compositions containing one or more of these 1H-imidazole derivatives as active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders in which cannabinoid receptors are involved.The compounds have the general formula (I)wherein R, R1-R4and X have the meanings given in the specification.

REFERENCES:
patent: 2004/0214855 (2004-10-01), Carpino et al.
patent: 2005/0026983 (2005-02-01), Carpino

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