1H-imidazole-1-acetamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514212, 514326, 514397, 514400, 540603, 546210, 548336, 548341, 548342, C07D23361, C07D40112, C07D40312, A61K 31415

Patent

active

049621203

ABSTRACT:
N-[(alkylamino)alkyl]-4,5-diaryl-1H-imidazole-1-acetamides useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of a diaryl imidazole-1-acetic acid with an appropriate diamine.

REFERENCES:
patent: 4330544 (1982-05-01), Jarreau et al.
patent: 4410525 (1983-10-01), Jarreau et al.
Ezrin et al., FASEB Journal 2, A1557 (1988).
Iradyan et al., Chemical Abstracts 88:152498y (1978).
Iradvan et al., Chemical Abstracts 83:79153x (1975).
Abstract of EP 299,407, 1/18/89.

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