1H-cycloundeca[1,2-b:5,6-b']biscyclohepta(b)pyrans useful as ant

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

549220, 549382, A61K 3135, C07D31178

Patent

active

052848663

ABSTRACT:
A compound isolated from Eupricillium brefeldionum having the structure: ##STR1## is a useful antitumor agent.

REFERENCES:
patent: 4656192 (1987-04-01), Yamato
patent: 4833079 (1989-05-01), Kamei et al.
patent: 4883758 (1989-11-01), Kamei et al.
T. Nozie et al, "Synthesis of Puberulonic Acid", Faculty of Science, Tohoku University., V. 33 (1960), pp. 1071-1074.
M. Arakawa CA 62:972 (1965).
S. Matsumoto et al, CA 55:1921, (1960).
Quinn et al, "Quantitative Structure-Activity Relationships of Colchicines against P388 Leukemia in Mice", J. Med. Chem., 24 (1981), pp. 251-256.
Brossi et al, "Biological Effects of Modified Colchicines", 2. Evaluation of Catecholic Colchicines, Colchifolines, Colchicide, and Novel N-Acyl-and N-Aroyldeacetylcolchicines, J. Med. Chem., 26, (1983), pp. 1365-1369.
Yamato, "Antineoplastic Agent Claimed", 100, 105, 106, -Derwent 84-227823/37, (55-9134-720-A), (1984).
Yamato et al, "Synthesis of Tropolone Derivatives", J. Chem. Soc. Perkin Trans., (1984), pp. 1301-1304.
Yamato et al, "Synthesis and Antitumor Activity of Tropolone Derivatives. 3", J. Med. Chem., 29, (1986), pp. 1202-1205.
Weenen et al, "Lucidene, a Bis(bezopyranyl) Sesquiterpene from Uvaria lucida ssp. lucida", J. Org. Chem., 55, (1990), pp. 5107-5709.
The Merck Index, 10th ed. (1983) pp. 352 and 416.
Tatsuya Arai et al, "Structure of Fusariocin C, A Cytotoxic Metabolite from Fusarium Moniliforme", Agric. Biol. Chem., 45 (1981), pp. 1689-1692.
Yamato et al, "Synthesis and Antitumor Activity of Tropolone Derivatives. 7..sup.1 Bistropolones Containing Connecting Methylene Chains", J. Med. Chem., 35, (1992), pp. 267-273.
Harris et al, "Isolation and Structure Determination of Pycnidione, A Novel Bistropolone Stromelysin Inhibitor from a Phoma sp.", Tetrahedron., 49 (1993), pp. 2139-2144.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

1H-cycloundeca[1,2-b:5,6-b']biscyclohepta(b)pyrans useful as ant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1H-cycloundeca[1,2-b:5,6-b']biscyclohepta(b)pyrans useful as ant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1H-cycloundeca[1,2-b:5,6-b']biscyclohepta(b)pyrans useful as ant will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-698225

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.