1H-Benz[de]isoquinoline-2(3H)-acetic acid derivatives

Details 1H-Benz[de]isoquinoline-2(3H)-acetic acid derivatives 1H-Benz[de]isoquinoline-2(3H)-acetic acid derivatives

1979-11-08

1981-03-03

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

424258, 546 98, C07D22114, A61K 3147

Patent

active

042541093

ABSTRACT:
Herein disclosed are 6-substituted derivatives of 1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid. The derivatives inhibit lens aldose reductase.

REFERENCES:
patent: 3821383 (1974-06-01), Sestanj et al.
patent: 4118495 (1978-10-01), Lippman
Dvornik, Science 182, 1146 (1973).
Noguchi et al. C.A. 72, 56708r (1970).
Graushen et al. J. Het. Chem 11, 33 (1974).
Shirosaki, Chem. Abs. 86, 89467d (1977).

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