1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical c

Details 1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical c 1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical c

1987-07-02

1988-11-22

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546256, 546143, 546159, 546270, 544113, 544283, 544316, 514259, 514260, 514300, 514307, 514311, 514338, C07D51304, C07D41714, A61K 3144

Patent

active

047866454

ABSTRACT:
A compound of the general formula I: ##STR1## in which Ar is a pyridyl, quinolinyl, isoquinolinyl, naphthyridinyl, pyrimidyl, quinazolinyl, thiazolyl, benzothiazolyl, imidazolyl, benzimidazolyl, oxazolyl, benzoxazolyl, thienyl, benzothienyl or naphthyl group; optionally substituted with one or more halogen or alkyl, alkyloxy, alkylthio, trifluoromethyl, amino, alkylamino, dialkylamino, hydroxy, cyano, alkylsulphinyl, alkylsulphonyl, sulphamido, alkylsulphamido, dialkylsulphamido, alkylcarbonyl, benzoyl, alkyloxycarbonyl, carboxy, phenoxycarbonyl, alkylcabonyloxy, benzoyloxy, alkylcarbonylamino, benzamido, phenyl, benzyl, phenoxy or phenylthio group, provided that (i) when Ar is a pyridyl group, the pyridyl group must be substituted, (ii) an alkyl moiety contains 1 to 4 straight- or branched chain carbon atoms; (iii) a phenyl moiety may be unsubstituted or substituted with one or more halogen or alkyl, alkyloxy, alkylthio, trifluoromethyl, amino, alkylamino, dialkylamino, hydroxy, cyano, phenyl or benzyl group
in separate enantiomeric form or mixtures thereof, or a pharmaceutically acceptable salt thereof is useful in the treatment of all pathological conditions in which PAF-acether may be implicated directly or indirectly.

REFERENCES:
patent: 4529728 (1985-07-01), Fabre et al.

Affiliated with

Also associated with

Rating

1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical c does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical c, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical c will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-435573