1a-7-substituted derivatives of mitomycin and uses thereof

Details 1a-7-substituted derivatives of mitomycin and uses thereof 1a-7-substituted derivatives of mitomycin and uses thereof

1985-06-06

1988-01-19

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

514908, 536 173, 536 174, 536 187, 536 22, 548422, C07D48714, A61K 2100, A61K 3140

Patent

active

047205431

ABSTRACT:
This invention discloses 1a- and 7-substituted derivatives of mitosanes containing thiocarbamoyl and glycosyl residues. The compounds possess antibacterial and antitumor activity, with a concomitant reduction in bone marrow toxicity as compared to the parent compounds.

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