19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs there

Details 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs there 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs there

1975-06-16

1976-03-23

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603974, 424238, C07J 100

Patent

active

039460525

ABSTRACT:
19-Norpregna-1,3,5(10)-trien-3-ol and loweralkyl homologs thereof wherein the alkyl group attached in the 17.beta. position contains from 2 to 7 carbon atoms. Said compounds, along with the corresponding known 17.beta.-methyl derivative, are found to have antifertility activity, and particularly postcoital antifertility activity, along with very low estrogenic activity, when administered orally to mammals.

REFERENCES:
U.S. Department of HEW, National Institute of Health, Endocrine Bioassay Data, Uterotropic, Issue 3, June 1968, p. 113.

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