19-Hydroxy PGE.sub.1 carbinol analogues

Details 19-Hydroxy PGE.sub.1 carbinol analogues 19-Hydroxy PGE.sub.1 carbinol analogues

1978-03-17

1978-11-28

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

568598, 568845, 2604381, C07C17700

Patent

active

041276124

ABSTRACT:
19-Hydroxy carbinol analogues of PGE.sub.1 having the structure ##STR1## are disclosed as bronchodilators. Methods of preparing the analogues are also disclosed.

REFERENCES:
patent: 4054595 (1977-10-01), Marx et al.
FEBS Letters, 57, 22 (1975).
Science, 187, 1093 (1975).
Sih, Prostaglandins, 13,830 (1977).

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