19-Hydroxy-19-methyl-PGI.sub.2 compounds

Details 19-Hydroxy-19-methyl-PGI.sub.2 compounds 19-Hydroxy-19-methyl-PGI.sub.2 compounds

1979-07-05

1980-09-30

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603452, 26034673, 260556A, 260556AR, 2605705CA, 260573, 260574, 260577, 260584R, 260584A, 542416, 542421, 542422, 542426, 542431, 548250, C07D30793

Patent

active

042255074

ABSTRACT:
Prostacyclin and prostacyclin-type derivatives having a 19-hydroxy feature are disclosed, including processes for preparing them and the appropriate intermediates.
The compounds are useful for pharmacological purposes such as inhibition of blood platelate aggregation.

REFERENCES:
Johnson, J. Am. Chem. Soc. 100, 7690-7704 (1978).

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