19,8-Lactone steroid derivatives and processes of preparation th

Details 19,8-Lactone steroid derivatives and processes of preparation th 19,8-Lactone steroid derivatives and processes of preparation th

1976-07-09

1978-07-25

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023957, C07J 7100

Patent

active

041028830

ABSTRACT:
There are provided novel 19,8-lactone and lactol steroids derivatives having the formula ##STR1## wherein A and B represent 14- or 15-carbon atoms, respectively, which are either linked by a double bond, or which carry an .alpha.- or .beta.-oxido or a 14.alpha.- or .beta.-hydroxy group in which case B is a methylene group; Y is .dbd.O; 3.alpha. or 3.beta.-OH;.sup.2 H;.sup.3 H; O-alkyl; or O-acyl; H; R' is OH, .dbd.O or acetoxy, the 5-hydrogen atom is either in the .alpha. or .beta.-position; there is an optional double bond in position 4(5); 5(6) and 6(7); and R is selected from the group consisting of O-acyl; ##STR2## AND CN, wherein alkyl is tetrahydropyranyl, lower alkyl, preferably methyl or ethyl, or a substituted methyl wherein the substituent is selected from the group consisting of phenyl, halogen, preferably chlorine and bromine, methoxy, CH.sub.2 .dbd.CH and HC.tbd.C; acyl represents a group selected from those consisting of acetate, trilower-alkyl acetates wherein the lower alkyl group is preferably methyl or ethyl, monohalo acetates and trihalo acetates, preferably wherein the halogen is chlorine and bromine. Several processes for preparing such novel compounds are disclosed, which compounds are useful as intermediates in the preparation of further compounds.

REFERENCES:
patent: 3849402 (1974-11-01), Kruger

Affiliated with

Also associated with

Rating

19,8-Lactone steroid derivatives and processes of preparation th does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 19,8-Lactone steroid derivatives and processes of preparation th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 19,8-Lactone steroid derivatives and processes of preparation th will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1420562