[18F]-furanosylpurine derivatives and uses thereof

Details [18F]-furanosylpurine derivatives and uses thereof [18F]-furanosylpurine derivatives and uses thereof

2007-09-25

2007-09-25

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Reexamination Certificate

active

10831626

ABSTRACT:
2′-Deoxy-2′-[18F]-labeled and 3′-deoxy-3′-[18F]-labeled purine nucleoside analogs such as [18F]-FAA and [18F]-FXA have been found to have desirable properties for use as imaging agents. The analogs are particularly useful for in vivo imaging of biological material including organ tissues (e.g., heart, liver, brain and kidneys) and tumors. Methods for the preparation of the [18F]-FAA and [18F]-FXA are also provided.

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Van Den Boogaart et al. Eur. J. Biochem. 1994, 221, 759-768.

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