18891, a novel human lipase

Details 18891, a novel human lipase 18891, a novel human lipase

2005-03-08

2005-03-08

Monshipouri, Maryam (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

C435S198000, C435S006120, C435S252300, C435S325000, C435S320100, C530S350000

Reexamination Certificate

active

06864064

ABSTRACT:
The present invention relates to a newly identified human lipase belonging to the family of mammalian lipases. The invention also relates to polynucleotides encoding the lipase. The invention further relates to methods using the lipase polypeptides and polynucleotides as a target for diagnosis and treatment in lipase-mediated or -related disorders. The invention further relates to drug-screening methods using the lipase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the lipase polypeptides and polynucleotides. The invention further relates to procedures for producing the lipase polypeptides and polynucleotides.

REFERENCES:
patent: 6150502 (2000-11-01), Strachan et al.
patent: 6605592 (2003-08-01), Ni et al.
patent: WO 9824888 (1998-06-01), None
patent: WO 9955865 (1999-11-01), None
patent: WO 0056751 (2000-09-01), None
Murthy et al., “Molecular Pathobiology of the Human Lipoprotein Lipase Gene”, Pharmacol. Ther., 1996, pp. 101-135, vol. 70, No. 2, Elsevier Science, inc.

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