180 kD protein that interacts with protein histidine...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C435S196000

Reexamination Certificate

active

07432348

ABSTRACT:
180 KDa protein histidine phosphatase interacting protein (PHPIP-180) polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PHPIP-180 polypeptides and polynucleotides in diagnostic assays.

REFERENCES:
patent: 2003/0212257 (2003-11-01), Spytek et al.
patent: WO 02081629 (2002-10-01), None
Revised Interim Written Description Guidelines Training Materials, http://www.uspto.gov/web/offices/pac/writtendesc. pdf, pp. 27-29, printed on Oct. 17, 2006.
Nagase T et al., “Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro,” DNA Research 2000, pp. 65-73, vol. 7, XP000923011, The DNA and polypeptide sequences of KIAA1365 comprise the sequences of SEQ IDs No. 1 and 2 repectively, abstract.
Apperson Michelle L II Soo Moon et al., “Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family,” Journal of Neuroscience, 1996, pp. 6839-6852, vol. 16, No. 21, XP002247309, ISSN: 0270-6474, abstract.
Strack Stefan et al., “Association of calcium/calmodulin-dependent kinase II with developmentally regulated splice variants of the postsynaptic density protein densin-180,” Journal of Biological Chemistry, Aug. 18, 2000, pp. 25061-25064, vol. 275, No. 33, ISSN: 0021-9258, abstract.
Walikonis Randall S et al., “Densin-180 forms a temary complex with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin,” Journal of Neuroscience, Jan. 15, 2001, pp. 423-433, vol. 21, No. 2, XP002247311, ISSN: 0270-6474, the whole document.
Izawa Ichiro et al., “Densin-180 interacts with delta-catenin
eural plakophilin-related armadillo repeat protein at synapses,” Journal of Biological Chemistry, Feb. 15, 2002, pp. 5345-5350, vol. 277, No. 7, XP002247312, ISSN: 0021-9258, the whole document.

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