Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-09-02
1981-10-06
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
26023955C, 26039747, 2603973, 26039745, 424243, C07J 500, A61K 3156
Patent
active
042935482
ABSTRACT:
Progesterone derivatives having a vinylidene or a 1-alkynyl substituent at the 18-position and further optionally hydroxylated at the 11-position and the 21-position are described herein. Compounds having both an ethynyl substituent and a hydroxy substituent at the 18-position are also described herein. The compounds are useful as aldosterone inhibitors.
REFERENCES:
patent: 3796728 (1974-03-01), Tanabe
patent: 3842074 (1974-10-01), Anner et al.
patent: 4052421 (1977-10-01), Biollaz et al.
R. Van Moorselaar et al., "Rec. Trav. Chim. Pays-Bas," 88 (1969) pp. 737-751.
Johnston J. O'Neal
Metcalf Brian W.
Kolano John J.
McDonald Raymond A.
Merrell Dow Pharmaceuticals Inc.
Roberts Elbert L.
Stein William J.
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