Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2007-06-28
2010-12-07
Badio, Barbara P (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C540S041000
Reexamination Certificate
active
07846917
ABSTRACT:
The present invention describes the novel 18-methyl-19-norandrost-4-ene 17,17-spiro ethers of the general formula Iin whichZ is an oxygen atom, two hydrogen atoms, a group ═NOR or ═NNHSO2R, where R is a hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 or 3 to 4 carbon atoms,R4is a hydrogen atom, a halogen atom or a trifluoromethyl group,and R6and/or R7may have α or β configuration, and R6and R7are independently of one another a hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 or 3 to 4 carbon atoms or a straight- or branched-chain alkenyl group having 2 to 4 or 3 to 4 carbon atoms or a saturated cycloalkyl group having 3 to 5 carbon atoms or together are a methylene group or a double bond.The novel compounds have progestational and antimineralocorticoid activity.
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Bohlmann Rolf
Borden Steffen
Gallus Norbert
Huebner Jan
Kuhnke Joachim
Badio Barbara P
Bayer Schering Pharma AG
Millen White Zelano & Branigan P.C.
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