18-Methyl-19-nor-20-ketopregnanes and process for the preparatio

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424243, 2603973, 2603974, 26039745, C07J 500, A61K 3156

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active

040297772

ABSTRACT:
18-Methyl-19-nor-20-keto steroids of the formula ##STR1## wherein R.sub.1 and R.sub.2 collectively are an oxygen atom, or each is hydrogen, or one of R.sub.1 and R.sub.2 is hydrogen and the other is hydroxy, and R.sub.3 is a ketonic oxygen atom or two hydrogen atoms, possess CNS-depressant activity, especially anesthetic-narcotic activity.

REFERENCES:
patent: 3822297 (1974-07-01), Phillipps et al.
patent: 3822298 (1974-07-01), Clayton et al.

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