Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2007-04-03
2007-04-03
Badio, Barbara P. (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C552S611000
Reexamination Certificate
active
11104736
ABSTRACT:
New 17α-fluorosteroid compounds of formula (I) are disclosed:wherein R1denotes H or methyl; R2and R3each denote H, Cl or methyl; and either a double bond or a single bond is present between C-6 and C-7 and also C-9 and C-10 of the steroid ring system respectively. These compounds have an activity profile with hybrid character so that they act as inhibitors for 5α-reductase and as high potency gestagens. Pharmaceutical compositions containing them are disclosed. They are suitable for treatment of conditions, which are caused by high levels of androgen in organs and tissues. These new compounds can be used in combination with other hormonal substances, such as estrogens, testosterone and other androgens, as contraceptives and for other applications.
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Bothe Ulrich
Droescher Peter
Elger Walter
Hillisch Alexander
Menzenbach Bernd
Badio Barbara P.
Schering AG
Striker Michael J.
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