17-spiromethylene steroids

Details 17-spiromethylene steroids 17-spiromethylene steroids

1997-11-03

1998-12-29

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514379, 514403, 514462, 540 9, 540 23, 540 28, 548241, 548242, 5483575, 549331, 549332, A61K 3158, A01N 4380, C07J 2100, C07J 7100

Patent

active

058542353

ABSTRACT:
The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein R.sub.a and R.sub.b are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17.alpha. of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.

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