17-spiromethylene steroids

Details 17-spiromethylene steroids 17-spiromethylene steroids

1993-07-28

1998-01-27

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

540 23, 540 28, C07J 2100, C07J 4100, C07J 4300, A61K 3158

Patent

active

057122644

ABSTRACT:
The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein R.sub.a and R.sub.b are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17.alpha. of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.

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