17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF.sub.1.beta. comp

Details 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF.sub.1.beta. comp 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF.sub.1.beta. comp

1976-11-12

1977-12-27

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260520B, C07C 6976

Patent

active

040656314

ABSTRACT:
The disclosure includes novel compounds which differ from the known prostaglandins PGF.sub.2.alpha., PGF.sub.2.beta., PGE.sub.2, PGA.sub.2, and PGB.sub.2 in that the carbon-carbon double bond in the carboxyl-terminated chain of the novel compounds is in the 4,5-position rather than in the 5,6-position, and in that there is a phenyl or substituted phenyl group in the other chain of the novel compounds. These novel compounds are useful for a variety of pharmacological purposes, including abortion, labor induction, and reduction of gastric secretion.

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