17-Nor-6-methyl-steroids

Details 17-Nor-6-methyl-steroids 17-Nor-6-methyl-steroids

1974-06-13

1976-04-27

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603974, 2603975, 424242, C07J 100

Patent

active

039534839

ABSTRACT:
Novel steroid compounds are provided represented by the formula: ##SPC1##
Wherein each of R.sup.1 and R.sup.2 represents hydrogen or methyl group or R.sup.1 and R.sup.2 may be combined with each other to represent methylene group, n is 2 or 3 and the dotted line means a double bond at 6-exo-position when n is 2 or between 6- and 7-position when n is 3.
These novel compounds show a strong anti-androgenic activity, especially by oral administration, and can be used as a remedy for the prostatomegaly.

REFERENCES:
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patent: 3117966 (1964-01-01), Petrow
patent: 3127396 (1964-03-01), Wiechert et al.
patent: 3356694 (1967-12-01), Lunn
patent: 3497498 (1970-02-01), Georgian
patent: 3655649 (1972-04-01), Habermehl et al.
patent: 3679715 (1972-07-01), Beaton et al.
Burn et al., Chem. and Ind., Nov. 3, 1962, pp. 1907-1908.
Fetizon et al., Chem. Abstracts, 58:14043f.

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