Organic compounds -- part of the class 532-570 series – Organic compounds – Cyclopentanohydrophenanthrene ring system containing
Reexamination Certificate
2005-02-15
2005-02-15
Qazi, Sabiha N. (Department: 1616)
Organic compounds -- part of the class 532-570 series
Organic compounds
Cyclopentanohydrophenanthrene ring system containing
C552S527000, C552S530000, C514S169000, C514S171000, C514S177000
Reexamination Certificate
active
06855836
ABSTRACT:
The invention relates to 17-methylene steroids, process for their production and pharmaceutical compositions that contain these compounds.The compounds according to the invention have a hybrid-type profile of action in the sense that they act as inhibitors of 5α-reductase and simultaneously as gestagens. They are therefore suitable for treating diseases that are the result of elevated androgen levels in certain organs and tissues in men and women. Together with other hormonal substances, such as an estrogen, testosterone or a strong androgen, the compounds according to the invention are suitable as contraceptive agents for women and for men.
REFERENCES:
patent: 2769823 (1956-11-01), Schneider et al.
patent: 2789989 (1957-04-01), Julian et al.
patent: 2802015 (1957-08-01), Colton
patent: 5194602 (1993-03-01), Batisi et al.
Barnikol-Oettler et al. (AN CA62:11871e, CAOLD, DN 62:66733, HCAPLUS, abstract of J. Prakt. Chem. (1965), 27(1-2), 18-23).*
AN CA51:18017b, CAOLD, DN 62:66733, HCAPLUS, abstract of US Patent 2802015.*
AN CA51:12161f, CAOLD, abstract of US 2789989.*
.AN CA51:8821c, CAOLD, abstract of US Patent 2769823.
Droescher Peter
Elger Walter
Hillisch Alexander
Kaufmann Gunter
Menzenbach Bernd
Jenapharm GmbH & Co. KG
Millen White Zelano & Branigan P.C.
Qazi Sabiha N.
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